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Research Publications

The O’Brien Laboratory is working to understand the nutritional, endocrine, and genomic factors that interact to regulate calcium, vitamin D, and iron homeostasis. Our publications cover a wide range of topics, including the use of stable mineral isotopes as tracers in our studies. Learn more about our research and findings below.

Recent Publications

  1. Park CY, Barad A, Gu Z, Bender E, Pressman EK, Clark A, O’Brien KO. Dietary Intake in East Asians and Northern European Participants from the FeGenes Study. Eur J Nutr 2025 Jun 5;64(5):205. doi: 10.1007/s00394-025-03730.

  2. Barad A, Xu Y, Bender E, Pressman EK, Gu Z, O’Brien KO. Differences in non-heme iron absorption between healthy adults of East Asian or Northern European ancestry from the Iron Genes in East Asian and Northern European Adults Study (FeGenes). Am J Clin Nutr 2025; 121(2):417-46. Published along with an editorial Am J Clin Nutr  2025 121(2):189-90.

  3. Barad A, Xu Y, Bender E, Pressman EK, Gu Z, O’Brien KO. Iron regulatory hormones and their associations with iron status biomarkers among healthy adults of East Asian or Northern European ancestry: A cross-sectional analysis from the Iron Genes in East Asian and Northern European Adults Study (FeGenes).Am J Clin Nutr 2025; 121(2):406-416. Published along with an editorial Am J Clin Nutr 2025 121(2):189-90.

  4. Barad A, Xu Y, Bender E, Kang W, Gu Z, Pressman EK, O’Brien KO. Characterization of iron status biomarkers and hematological indices among young adults of East Asian or Northern European ancestry: A cross-sectional analysis from the Iron Genes in East Asian and Northern European Adults Study (FeGenes). Am J Clin Nutr 2024; 121(2):394-405. Published along with an editorial Am J Clin Nutr  2025 121(2):189-90.

  5. Barad, A. Clark AG, Pressman EK, O’Brien KO.  Associations between genetically predicted iron status and cardiovascular disease risk: A Mendelian randomization study. J Am Heart Assoc 2024; 12(11):e034991.

  6. Archundia-Herrera C, Nunes F, Barrios ID, Park CY, Bell RC, O’Brien KO. Development of a Database for the Estimation of Heme Iron and Non-Heme Iron Content of Animal-Based Foods. Curr Dev Nutr 2024; 8(4):102130.

  7. Barad, A. Clark AG, Pressman EK, O’Brien KO.  Associations between genetically predicted iron status and cardiovascular disease risk: A Mendelian randomization study. medRxiv 2024; 6:2024.02.05.24302373.

  8. O’Brien KO, Pressman EK. Reply to M Jefferds et al., Longitudinal Hemoglobin Data in U.S. Pregnant Women. Am J Clin Nutr 2024; 119(1):234-235.

  9. Barad A, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O’Brien KO. Placental Ferroportin Protein Abundance is Associated with Neonatal Erythropoietic Activity and Iron Status in Newborns at High Risk for Iron Deficiency and Anemia. Am J Clin Nutr 2024; 119(1):76-86.

  10. O’Brien KO, Wang Y. The Placenta: A Maternofetal Interface. Annu Rev Nutr 2023; Aug 21:43:301-325.

  11. Barad A, Clark AG, Pressman EK, O'Brien KO. Associations Between Genetically Predicted Iron Status and Cardiovascular Disease Risk: A Mendelian Randomization Study. J Am Heart Assoc. 2024 Jun 4;13(11):e034991. (PDF Link)

  12. Archundia-Herrera MC, Nunes F, Barrios ID, Park CY, Bell RC, O'Brien KO. Development of a Database of Heme Iron and Nonheme Iron Content of Animal-Based Foods. Curr Dev Nutr. 2024 Mar 3;8(4):102130. (PDF Link)

  13. Barad A, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O’Brien KO. Placental Ferroportin Proten Abundance is Associated with Neonatal Erythropoietic Activity and Iron Status in Newborns at High Risk for Iron Deficiency and Anemia. Am J Clin Nutr 2024; 119(1):76-86. (PDF Link)

  14. O’Brien KO, Wang Y. The Placenta: A Maternofetal Interface. Annu Rev Nutr 2023; Aug 21:43:301-325. (PDF Link)

  15. Delaney KM, Barad A, Castillo L, Hasund CM, Guillet, R, Pressman EK, Katzman PF, Ganz T, Nemeth E, O’Brien KO. Placental erythroferrone and erythropoietin mRNA expression is not associated with maternal or neonatal iron status. J Nutr 2023; May 28:S0022-3166(23)72116-0. (PDF Link)

  16. Park CY, Lei X, O’Brien, KO. Why bioenhanced foods: role of food-based supplementation of bioactive micronutrients in public nutrition and health. Precision Nutrition, 2023; June 2(2), e00041. (PDF Link)

  17. Kang, W, Irvine, C, Wang Y, Clark A, Gu, Z, Pressman EK, O’Brien KO. Hemoglobin Distributions and the Prevalence of Anemia in a Multiethnic US Pregnant Population. AJCN 2023; 117(6):1320-30. Published along with an editorial; Iron deficiency in Pregnancy: A health inequity. Am J Clin Nutr 2023; Jun; 117(6):1059-60. (PDF Link 1; PDF Link 2)

  18. O’Brien KO. Maternal, Fetal and Placental Regulation of Placental Iron Trafficking. Placenta 2022; 125:47-53. (PDF Link)

  19. Delaney KM, Cao Chang, Guillet R, Pressman EK, O’Brien KO. Fetal Iron Uptake from Recent Maternal Diet and Red Blood Cell Catabolism. Am J Clin Nutr 2022; 1;115(4):1069-79. Published along with an accompanying editorial; Fairweather-Tait. How much iron does a healthy pregnant woman require? AJCN 2022; 00:1-2. (PDF Link 1; PDF Link 2)

  20. Best CM, Sherwood R, Novotny JA, Zhang S, Pressman EK, O’Brien KO. Vitamin D3 kinetics in nonpregnant and pregnant women after a single oral dose of trideuterated vitamin D3. J Steroid Biochemistry and Molecular Biology, 2022; Feb 216:106034. (PDF Link)

  21. Barad A, Guillet R, Pressman EK, Katzman PJ, Miller RK, Darrah TH. Placental Iron Content is Lower than Previously Estimated and is Associated with Maternal Iron Status in Women at Greater Risk for Gestational Iron Deficiency and Anemia. J Nutr 2022; Mar 3: 152(3):737-746. (PDF Link)

  22. Delaney KM, Guillet R, Pressman EK, Ganz T, Nemeth E, O’Brien KO. Umbilical cord erythroferrone is inversely associated with hepcidin but does not capture the most variability in iron status of neonates born to teens carrying singletons and women carrying multiples. J Nutr 2021; 4:151(9):2590-2600.  Published along with an editorial: Kling PJ. Ironing out the details of maternal-fetal iron trafficking: New Tools in the Toolbox. J Nutr 2021; 151(9):2509-2510. (PDF Link 1; PDF Link 2)

 

Complete List of Published Work in

MyBibliography: http://www.ncbi.nlm.nih.gov/sites/myncbi/kimberly.o'brien.1/bibliography/47582544/public/?sort=date&direction=ascending

Where to find us 

Our Laboratory is located on the Cornell Ithaca campus in The Human Metabolic Research Unit (HMRU) in Martha Van Rensselaer Hall .   

Martha Van Rensselaer (MVR) Hall

Room 2151 and 2152, West Wing

Cornell University

Ithaca, NY 14850

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